Isolation , Partial Characterization of a Dihydroflavonol From Sudanese Wetheria indica L.(Sterculiaceae) Stems and Biological Activity of the Ethanol Extract

  • Mohamed Abdel Karim Sudan University of Science and Technology
  • Nousiba,M. Sudan University of Science and Technology
  • Dalia,O. Sudan University of Science and Technology
Keywords: Cistanch phelypea, Isolation, Dihydroflavonol, Antibacterial Activity, Antioxidants Activity

Abstract

Phytochemical screening of Wetheria indica stems revealed the presence of flavonoids, tannins steroids , saponins and alkaloids. A flavonoid - compound (I)- was isolated from ethanol extract by thin layer chromatography and its structure was partially characteized on the basis of its spectral data (IR, UV, NMR ). The ethanol extract of Wetheria indica stems was evaluated for antimicrobial activity and it showed moderate activity against all test organisms. Also the extract exhibited significant free radical scavenging capacity.

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Author Biographies

Mohamed Abdel Karim, Sudan University of Science and Technology
Nousiba,M., Sudan University of Science and Technology
Dalia,O., Sudan University of Science and Technology

References

Eisenberge,D.M., Kesler,R.C., Foster,C., Norlock,F.E., Calkinsand,D.R. and T.L. Delbanco,T.L , Unconventional Medicine in the United States: Prevalence, costs and Patterns of use. N. Engl. J. Med., 1998,328: 246-252.

Hostettmann,K., Marston,A., Ndojoko,K. and J. Wolfender,J. , The potential of Africa Plants as a source of drug , Curr. Organic Chem.,2000, 4: 973-1010

Kone,M., Ouattara,K., Ghahoue,A. and A. Coulibaly,A., ,Study ethnopharmacological and phytochemical screening of some plants involved in the treatment of abdominal infections in the department of kouto. Sch., J. App. Med. Sci.,2013,1(2):56-61

Olajuyigbe,O., Babalola,A.E. and A.J. Afolayan,A.J. , Antibacterial and phytochemical screening of crude ethanolic extracts of Waltheria indica Linn. African Journal of Microbiology Research,2011, 5: 3760-3764.

Silva Junior, A.A,Vizotto,,V.J., Giongi,E., Macedo,S.G. and L.F. Marques , Plantas medicinais, caracterização e cultivo.EPAGRI. Bol. Técnico Florianópolis,1994, 68: 1-71.

Batawila,K., Kakou,K., Koumaglo, M., Gbeassor, B. De Foucault, P. Bouchet and K. Akpagana , Antifungal activities of five combretaceae used in Togolese traditional medicine, Fitoterapia,2005,76: 264-268

Jansen, O.; Angenot, L., Tits, M., Nicolas, J. P., De Mol, P. ,Nikiema, J. B.; Frederich, M. J. , Ethnopharmacol.,2010, 130, 143−150.

Bala, A. Y. , Adamu, T. , Abubakar, U., Ladan, M. J. , Abubakar, M.G. ,Niger. J. ,Basic Appl. Sci. ,2009,17, 257−264.

Santangelo C, Varì R, Scazzocchio B, Di Benedetto R, Filesi C, Masella R. Polyphenols, intracellular signaling and inflammation , Ann Ist Super Sanità, 2007, 43(4): 394 – 405

Matsuda H., Morikawa T., Ando S., Toguchida I., Yoshikawa M., Bioorg. Med. Chem., 2003, 11, 1995—2000.

Flatie T, Gedif T, Asres K, Gebre-Mariam T. , Ethnomedical survey of Bretha ethnic group Assosa

zone, Benishangul - Gumuz regional state, midwest Ethiopia. (Medicinal plants reported by household respondents of Berta ethnic group). J Ethnobiology and Ethnomedicine,2009, 5:14 : doi:10.1186/1746-4269-5-14

Gamble J. S., “Flora of the Presidency of Madras,” Vol. 2,1995, Botanical Survey of India, Calcutta, p. 79.

.Vedavathy S., Rao K. N., Indian Drugs,1995, 32, 427-432 .

Thammanna T., Rao K. N., Chetty K. M. “Angiospermic Wealth of Tirumala,” ,1994, TTD Publication, Tirupati, p.19.

Sukhdev. S. H; Suman. P. S. K; Gennaro. L and Dev. D. R " Extraction technologies for medicinal and aromatic plants" ,2008, United Nation Industrial Development Organization and the International Center for Science and High Technology. pp 116.

Harborne, J. B. , Phytochemical methods. 2nd edition.1984, Chapman and Hall.

.Martinez A, Valencia G: Marcha fitoquimica : In "Manual de prácticas de Farmacognosia Fitoquímica" , 1999. 1st edition, Medellin: Universidad de Antioquia; Phytochemical screening methods 59-65.

Wall, M. E. , Eddy, C. R., McClenna, M. L. and Klump, M. E. , Detection and estimation of steroid and sapogenins in plant tissue , Analytical Chemistry,1952, 24:1337-1342.

Sofowora, A. "Medicinal Plants and Traditional Medicines in Africa" ,1993, John, Willey & Sons,New York, P. 256

Shimada. K, Fujikawa.K, Yahara. K, Nakamura.T, Antioxidative properties of xanthan on the antioxidation of soybean oil in cyclodextrin emulsion. J Agric food Chem ,1992, 40:945-8

Published
2019-08-30
How to Cite
Karim, M. A., Nousiba,M., & Dalia,O. (2019). Isolation , Partial Characterization of a Dihydroflavonol From Sudanese Wetheria indica L.(Sterculiaceae) Stems and Biological Activity of the Ethanol Extract. IJRDO - JOURNAL OF BIOLOGICAL SCIENCE, 5(8), 09-16. https://doi.org/10.53555/bs.v5i8.3167